Digital Study Design

ObvioHealth’s experts understand how to design your trial to recruit and train the optimal cohort and root out statistical “noise”—so you get the robust evidence you need.

Poor Study Design Can Tank Your Trial’s Success

Problem: 54% of trials fail in clinical development*

Factors most likely to drive poor results are flawed study design, wrong choice of endpoint, and inadequate sample size*

*See analysis of 640 Phase III trials by Hwang et. al.

Solution: Digital study design expertise that powers your study for success.

Efficient trials minimize participant burden and maximize data accuracy.

Scientific experience, digital expertise

ObvioHealth’s in-house team of clinicians, data scientists, and engineers work in tandem with sponsors and CROs to design digital trials that ensure data integrity. Smoother, more efficient participant and site workflows result in more streamlined study conduct.

Endpoint Identification

Instrument Selection

Patient Training

Patient Journey Optimization

Clinical Endpoint and Outcome Selection

Merging clinical science with data science to determine the best endpoints and outcomes for a given TA and protocol.

Root Your Endpoints in Science

Our research and scientific teams conduct comprehensive reviews to ensure the identification of the most relevant endpoints for each indication.

Pinpoint the Most Meaningful Metrics

Our deep understanding of patient context allows us to identify the most sensitive metric of therapeutic intervention and ensure measures represent real-life scenarios.

Instrument Selection and Validation

Providing recommendations for instruments that are technically and clinically valid as well as user-friendly.

Select the Optimal Instrument(s)

We identify instruments, devices, and wearables that are most appropriate for the population, condition, and treatment under study.

Evaluate the Tradeoffs

We arbitrate between the reduction of patient burden and the delivery of outcomes quality, taking into consideration fatigue, usability, and granularity of data.

Multi-vital devices can make life easier for patients. But, the more things get measured, the more the quality of the data tends to suffer. Instrument selection must determine the right balance between these sometimes conflicting criteria.


Reducing the bias, errors, and variability inherent in self-reporting and rater scoring.

Improve Data Quality

Patient and caregiver training reduces the biases and errors associated with self-reporting, while also mitigating placebo effect.

Keep Patients Engaged

Interactive multimedia training sets expectations and educates on best practices and how to use tools to improve data quality.

The Digital Expertise You Need

  • eCOA and ePRO Experts
  • UX Experts
  • Implementation Experts

ObvioHealth: Delivering Stronger Evidence

ObvioHealth launched one of the first-ever DCT platforms with a mobile app in 2017. Today, we’re a global industry leader delivering DCTs that generate stronger evidence.


Medication Adherence


ePRO Compliance




Faster Recruitment


Consented Participants
Average rates for ObvioHealth completed studies (versus industry benchmarks, where applicable)
Co-creating the future of clinical trials with these industry leaders.

Successful trial design for migraine medical device

The study required a long run-in period to ensure enrollment of participants with the right type of headache. Learn how we designed the study to keep participants engaged prior to active treatment.