Patient and caregiver using digital technology for remote monitoring at home.

Patient Monitoring & Clinical Support

Integrated Patient Monitoring for High-Touch Therapies

Bring digital monitoring, clinical support, patient engagement, and direct-to-patient operations together in one configurable solution.

ObvioHealth and SPRIM PRO help pharmaceutical and biotechnology companies design and manage patient-monitoring programs from late-stage clinical development through commercialization and post-market support.

Maintain visibility between visits, route defined events to the appropriate teams, and support patients without coordinating multiple technology and service providers.

Discuss Your Monitoring Program

Explore REMS Capabilities

One Integrated Partner

One partner for technology, clinical support, patient engagement, and direct-to-patient operations.

25+ Years of Experience

SPRIM PRO brings more than 25 years of clinical operations and patient-support experience.

Configurable by Therapy

Built around each therapy's monitoring, support, and operational requirements.

Development Through Post-Market

Support that can evolve from clinical development through commercialization and post-market programs.

Complex Therapies Require More Connected Monitoring

Specialty medicines, biologics, cell and gene therapies, and other high-touch treatments often require ongoing visibility beyond traditional clinical and care settings.

Sponsors need flexible ways to collect patient information, maintain oversight, coordinate follow-up, and support patients without creating additional burden for sites, providers, and internal teams.

57% of novel FDA drug approvals between 2000–2024 were specialty medicines.¹ ¹Knox SE, Brennan CH, Enright DE, Neumann PJ, Chambers JD. FDA Approvals of Specialty Drugs, 2000–2024. Health Affairs Scholar. 2026;4(2):qxag035.

Complex Requirements

Monitoring schedules, safety requirements, and support needs vary by therapy and patient population.

Close-up of a wrist-worn remote patient monitoring device

Fragmented Delivery

Technology, clinical services, logistics, and patient support are often managed by separate vendors.

Clinician providing remote telehealth support

Patient and Provider Burden

Frequent visits, disconnected communication, and complicated reporting requirements can make participation difficult.

Clinician conducting a virtual patient consultation

One Connected Patient Monitoring Solution

ObvioHealth and SPRIM PRO combine the technology and operational services required to design and deliver patient-monitoring programs around the needs of each therapy.

ObvioGo® Digital Platform

The technology layer for patient engagement, data collection, monitoring & workflow routing.

ePRO, eCOA, eConsent, and remote data collection

Connected devices and wearable integrations

Telehealth and digital patient engagement

Centralized monitoring dashboards

Configurable alerts and workflow routing

Multilingual, patient-friendly experiences

SPRIM PRO Clinical Operations

The clinical and operational layer supporting patients, care teams & program execution.

Clinical and patient-support services

Patient education and engagement

Direct-to-patient device and supply logistics

Clinical review, follow-up, and triage support

Site and healthcare-provider coordination

Program documentation and sponsor reporting

One Partner. One Coordinated Program.

From Patient Signal to Clinical Action

1

Capture

Patient symptoms, ePRO/eCOA, device data, and other program-defined information can be captured remotely.

2

Monitor

Information flows into centralized digital monitoring workflows, giving clinical teams timely visibility into patient status.

3

Identify

Configured, program-defined thresholds help flag events and findings that meet criteria for clinical review.

4

Route

Program-defined events are directed to the appropriate clinical, safety, pharmacovigilance, or patient-support team.

5

Support

Clinical and patient-support teams can engage patients remotely when follow-up or intervention is required.

PURPOSE-BUILT FOR CAREGIVER–CHILD MONITORING

Capture the Full Caregiver–Child Picture

Pediatric rare disease and pediatric oncology programs often depend on data reported by a caregiver on behalf of a child, including data collected through REMS or other structured monitoring schedules. Getting that data right takes workflows designed around two connected roles—the caregiver and the child—rather than a single-patient model adapted after the fact.

ObvioHealth and SPRIM PRO bring years of hands-on experience designing caregiver-inclusive data collection for infant, early-childhood, and pediatric research. That experience shapes how we configure monitoring, attribute each data point to the right respondent, and support families for the program's full duration.

Connected Dyad Workflows

Monitoring built to capture input from both the caregiver and child, keeping each entry tied to the correct respondent and program requirement.

Clear Data Attribution

Every entry is attributed to its source — caregiver or child — so program teams can trust where each data point came from.

Pediatric Research Expertise

Study design and field teams with direct experience running infant, early-childhood, and pediatric research programs.

Built for Complex, High-Touch Therapies

ObvioHealth and SPRIM PRO configure digital monitoring, clinical support, and patient services around each therapy's clinical and operational requirements.

REMS Programs

Program-defined monitoring, documentation, and patient-support workflows designed around REMS requirements.

Rare Disease & Pediatric Oncology

Caregiver-inclusive data collection and monitoring for pediatric rare disease and oncology programs.

Advanced Biologics & Cell/Gene Therapies

Remote and in-person monitoring for complex administration, safety, and observation needs.

Specialty Pharmaceuticals

Digital monitoring and patient support for therapies requiring consistent, ongoing follow-up.

Infusion Therapies

Monitoring and support aligned with scheduling, administration, and post-infusion follow-up.

Patient Support Programs

Digital engagement, clinical operations, logistics, and care-team coordination in one program.

Discuss Your Monitoring Program

REMS & ENHANCED MONITORING

Extend Visibility Between Required REMS Touchpoints

Risk Evaluation and Mitigation Strategies (REMS) programs increasingly call for structured monitoring, pharmacovigilance, and follow-up alongside required in-person elements of care. ObvioHealth and SPRIM PRO provide the digital monitoring, clinical support, and patient engagement capabilities sponsors can build REMS-aligned programs around.

Remote monitoring capabilities are designed to complement, not replace, required in-person observation and other mandated REMS activities, giving clinical teams additional visibility between and around those touchpoints.

MONITOR

Structured, program-defined monitoring schedules aligned to REMS requirements.

ePRO, eCOA, and connected device data captured directly from patients between required in-person visits.

Centralized digital dashboards giving clinical and safety teams timely visibility into monitoring data.

RESPOND

Configurable alerts and routing workflows that direct program-defined information to the appropriate team.

Patient engagement and support designed to help maintain adherence to program requirements.

Telehealth and remote follow-up when program-defined criteria are met.

COORDINATE

Coordination support for required in-person REMS activities and site visits.

Documentation and reporting workflows to support program-level oversight.

Dedicated clinical operations and logistics support from the SPRIM PRO team.

Discuss Your REMS Requirements

Support That Extends Across the Therapy Lifecycle

ObvioHealth and SPRIM PRO carry patient monitoring and clinical support forward across four stages, from late-stage clinical development through post-market care.

Late-Stage Clinical Development

Digital monitoring and patient engagement built into late-stage clinical development programs.

Launch Preparation

Monitoring and patient-support infrastructure carried forward as a therapy approaches launch.

REMS & Enhanced Monitoring

Structured monitoring and clinical support aligned to REMS and other enhanced-monitoring requirements.

Post-Market Patient Support

Ongoing patient engagement and monitoring support that continues well beyond product launch.