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Cardiology Virtual Clinical Trials

Progressing cardiology research through better data

Cardiovascular disease takes an estimated 18 million lives per year, the leading cause of death worldwide, according to the World Health Organization. For some time in the United States, cardiovascular disease was on the decline. However, in recent years the trend has been ticking upward, as diseases like obesity, diabetes and hypertension become a growing problem.

Leading the way for potential transformative impact over the next decade is the convergence of digital health and analytics.

ObvioHealth makes it easier to study CVD with seamless device integration, allowing participants to take blood pressure, heart rate, pulse ox and respiratory readings from their own homes, and the data flows directly to a central database where it is monitored remotely. This provides more frequent data, and often more accurate data since readings are often higher in a clinic due to participant nerves. 

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Medical device used to measure blood pressure.
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Measuring the impact of rice vinegar on blood pressure in prehypertensive adults

ObvioHealth deployed a targeted digital recruitment strategy to enroll 128 patients with a blood pressure of 120-139/80-89 mmHg. This hybrid study collected clinical safety and efficacy data from a diverse population

• 87% medication adherence
• 89% retention

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Virtual Research: 5 Advantages of the New Normal

The post-pandemic world of clinical research will offer a stark contrast to its predecessor. Companies that reconfigure their protocols to support a virtual trial model during the COVID-19 outbreak will find themselves ahead of the curve in the post-pandemic world.

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The ObvioHealth App

Our proprietary application brings clinical research into people’s homes, making it easier for them to participate, and easier for researchers to collect robust data sets which reflect real behaviors.

"Blood pressure reading" screen of the ObvioHealth app.
"Connecting to device" screen of the ObvioHealth app.

Curious how to take your cardiovascular study virtual?

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The Better Data Formula for Your Cardiovascular Study

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Recruitment is often a huge barrier to trial success particularly when factors like age, ethnicity, and gender correlate so strongly with the prevalence of heart disease. ObvioHealth uses digital targeting methods to find untapped and underrepresented populations. We identify the online behaviors that point to people with a positive pre-disposition for a specific trial and, because our studies are virtual, we are not geographically tied to a site location, enabling us to recruit in areas with greater density of specific populations.  

Once recruited, we enroll participants through virtual prescreening/screening and e-consent. This eliminates the burdensome cost of site retention and staffing requirements, and often shortens the recruitment period.  In addition, people are generally more willing to contribute to research, knowing they can participate from the comfort of their homes.  

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Outcomes Measurement

The ObvioHealth platform and app incorporate multiple data capture technologies to adapt to the needs of any given trial.  These include simple survey-type completion of questionnaires and diaries, image, video and audio capture and use of wearables. For example, digital blood pressure monitors are integrated into our proprietary platform for easy reading.  Our complementary data collection methods ensure more robust data based on real world outcomes.

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Logistics Management 

Our platform makes it easy to trigger, track and manage products and payment of incentives. ObvioHealth can reimburse participants with the stipend program that is fully virtual. We ship any needed study supplies or devices directly to the participant’s home.

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Medication Adherence & Adverse Events

An important advantage of ObvioHealth’s app is the real time remote monitoring of medication adherence and potential adverse events. Our escalating system of reminders and immediate AE/SAE detection make our studies safer, while also improving medication adherence.

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Higher compliance, higher retention, more accurate data

Our easy-to-use, convenient app makes it easier for participants to remain compliant. There is little to no time wasted travelling to clinical sites, so there are fewer drop-outs. All of this means that studies end on time or ahead of schedule. And because participants are able to report more real world and real time experiences, the resulting data is more accurate and reliable.