As a founding member of DTRA, ObvioHealth is committed to driving the future of decentralized clinical trials in the industry.
Skin health is hard to measure. Reporting on skin lesions is difficult for patients and so the data they provide is often inaccurate. Despite their best efforts, patients struggle to use dermatologic scales properly and their scores are often biased by perceptual factors. Evaluating the surface area, distribution, morphology, number, size and color or a lesion is highly subjective and vulnerable to interpretation bias.
ObvioHealth’s virtual trial design makes it easy for dermatology researchers to collect both subjective and objective data from participants. Our user-friendly app lets participants report outcomes without ever having to visit a clinic and our multiple data capture options incorporate both structured and unstructured real world data to ensure robust outcomes.
Measuring the Impact of a Plant-based Supplement on Skin Health
A global manufacturer of wellness products needed to analyze the consumer-perceived effectiveness of a dietary supplement among healthy women.
• 86% Medication Adherence
• 87% Retention
Diaper Rash: Developing Consumer-backed Claims
Participants were asked to complete digital questionnaires which assessed product usage and satisfaction in support of two new consumer-centric claims.
• 4 Months to Project Completion
• 300 Mothers Recruited in 2 Months
The ObvioHealth App
Our proprietary application brings clinical research into people’s homes, making it easier for them to participate, and easier for researchers to collect robust data sets which reflect real behaviors.
ObvioHealth studies are run on our purpose-built platform by our own in-house virtual team. This allows us to work seamlessly from protocol design all the way through to analysis and reporting.
Recruitment & Onboarding
Recruitment is often a huge barrier to trial success. ObvioHealth uses digital targeting methods to find untapped populations. We identify the online behaviors that point to a positive pre-disposition for a specific trial and, because our studies are virtual, we are not geographically tied to a site location.
Once recruited, we enroll participants through virtual prescreening/screening and e-consent. This eliminates the burdensome cost of site retention and staffing requirements, and often shortens the recruitment period.
Dermatology studies often need to stratify by skin type. Our agile digital recruitment enables us to quickly course-correct to fill under-represented samples.
The ObvioHealth platform and app incorporates multiple data capture technologies to adapt to the needs of any given trial. These include simple survey-type completion of questionnaires and diaries, image, video and audio capture and use of wearables.
The image capture feature is particularly well-suited to submission of skin lesion or irritation photos that central experts can then rate. For sponsors looking to distinguish the ‘noise’ from the efficacy signals, this unstructured data is extremely valuable. And we are increasingly using artificial intelligence, to assess and score these lesions with an objective eye.
Our platform makes it easy to trigger, track and manage products and payment of incentives. ObvioHealth can reimburse participants with the stipend program that is fully virtual. We ship any needed study supplies or devices directly to the participant’s home.
Medication Adherence & Adverse Events
An important advantage of ObvioHealth’s app is the real time remote monitoring of medication adherence and potential adverse events. Our escalating system of reminders and immediate AE/SAE detection make our studies safer, while also improving medication adherence.